Neural populations for maintaining body fluid balance

Pivotal role of β-intercalated cells in maintaining body fluid and electrolyte balance

Inactivation of the B1 proton pump subunit (ATP6V1B1) in intercalated cells (ICs) leads to type I distal renal tubular acidosis (dRTA), a disease associated with saltand potassium-losing nephropathy. Here we show that mice deficient in ATP6V1B1 (Atp6v1b1-/mice) displayed renal loss of NaCl, K+, and water, causing hypovolemia, hypokalemia, and polyuria. We demonstrated that NaCl loss originated ...

Local Anesthetic for Castration: Maintaining a Balance

regional anesthesia techniques) may reduce hypotension and hypercarbia from excessive anesthetic drugs and provide additional perioperative analgesia. Forty-two dogs were divided into 2 groups: group L received intratesticular lidocaine injections 5 minutes before surgical castration, and group S received an equal volume of saline. There were no significant differences in baseline heart rate (H...

Fluid balance and electrolyte distribution in the human body.

Renal β-intercalated cells maintain body fluid and electrolyte balance.

Inactivation of the B1 proton pump subunit (ATP6V1B1) in intercalated cells (ICs) leads to type I distal renal tubular acidosis (dRTA), a disease associated with salt- and potassium-losing nephropathy. Here we show that mice deficient in ATP6V1B1 (Atp6v1b1-/- mice) displayed renal loss of NaCl, K+, and water, causing hypovolemia, hypokalemia, and polyuria. We demonstrated that NaCl loss origina...

Maintaining osmotic balance with an aglomerular kidney.

The gulf toadfish, Opsanus beta, is a marine teleost fish with an aglomerular kidney that is highly specialized to conserve water. Despite this adaptation, toadfish have the ability to survive when in dilute hypoosmotic seawater environments. The objectives of this study were to determine the joint role of the kidney and intestine in maintaining osmotic and ionic balance and to investigate whet...